CovidV2, Ncbi, Merge, bibRecord, 001582

Clinical Characteristics of Children with Coronavirus Disease 2019 in Hubei, China.

Identifieur interne : 001582 ( Ncbi/Merge ); précédent : 001581; suivant : 001583

Clinical Characteristics of Children with Coronavirus Disease 2019 in Hubei, China.

Source :

Current medical science [ 2523-899X ] ; 2020.

RBID : pubmed:32207032

Abstract

Since December 2019, COVID-19 has occurred unexpectedly and emerged as a health problem worldwide. Despite the rapidly increasing number of cases in subsequent weeks, the clinical characteristics of pediatric cases are rarely described. A cross-sectional multicenter study was carried out in 10 hospitals across Hubei province. A total of 25 confirmed pediatric cases of COVID-19 were collected. The demographic data, epidemiological history, underlying diseases, clinical manifestations, laboratory and radiological data, treatments, and outcomes were analyzed. Of 25 hospitalized patients with COVID-19, the boy to girl ratio was 1.27:1. The median age was 3 years. COVID-19 cases in children aged <3 years, 3.6 years, and ≥6-years patients were 10 (40%), 6 (24%), and 9 (36%), respectively. The most common symptoms at onset of illness were fever (13 [52%]), and dry cough (11 [44%]). Chest CT images showed essential normal in 8 cases (33.3%), unilateral involvement of lungs in 5 cases (20.8%), and bilateral involvement in 11 cases (45.8%). Clinical diagnoses included upper respiratory tract infection (n=8), mild pneumonia (n=15), and critical cases (n=2). Two critical cases (8%) were given invasive mechanical ventilation, corticosteroids, and immunoglobulin. The symptoms in 24 (96%) of 25 patients were alleviated and one patient had been discharged. It was concluded that children were susceptible to COVID-19 like adults, while the clinical presentations and outcomes were more favorable in children. However, children less than 3 years old accounted for majority cases and critical cases lied in this age group, which demanded extra attentions during home caring and hospitalization treatment.

DOI: 10.1007/s11596-020-2172-6
PubMed: 32207032

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<author><name sortKey="Zheng, Fang" sort="Zheng, Fang" uniqKey="Zheng F" first="Fang" last="Zheng">Fang Zheng</name>
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<country xml:lang="fr">République populaire de Chine</country>
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<author><name sortKey="Liao, Chun" sort="Liao, Chun" uniqKey="Liao C" first="Chun" last="Liao">Chun Liao</name>
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<author><name sortKey="Fan, Qi Hong" sort="Fan, Qi Hong" uniqKey="Fan Q" first="Qi-Hong" last="Fan">Qi-Hong Fan</name>
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<author><name sortKey="Chen, Hong Bo" sort="Chen, Hong Bo" uniqKey="Chen H" first="Hong-Bo" last="Chen">Hong-Bo Chen</name>
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<author><name sortKey="Zhao, Xue Gong" sort="Zhao, Xue Gong" uniqKey="Zhao X" first="Xue-Gong" last="Zhao">Xue-Gong Zhao</name>
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<author><name sortKey="Xie, Zhong Guo" sort="Xie, Zhong Guo" uniqKey="Xie Z" first="Zhong-Guo" last="Xie">Zhong-Guo Xie</name>
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<author><name sortKey="Li, Xi Lin" sort="Li, Xi Lin" uniqKey="Li X" first="Xi-Lin" last="Li">Xi-Lin Li</name>
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<author><name sortKey="Chen, Chun Xi" sort="Chen, Chun Xi" uniqKey="Chen C" first="Chun-Xi" last="Chen">Chun-Xi Chen</name>
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<author><name sortKey="Lu, Xiao Xia" sort="Lu, Xiao Xia" uniqKey="Lu X" first="Xiao-Xia" last="Lu">Xiao-Xia Lu</name>
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<author><name sortKey="Liu, Zhi Sheng" sort="Liu, Zhi Sheng" uniqKey="Liu Z" first="Zhi-Sheng" last="Liu">Zhi-Sheng Liu</name>
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<author><name sortKey="Lu, Wei" sort="Lu, Wei" uniqKey="Lu W" first="Wei" last="Lu">Wei Lu</name>
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<country xml:lang="fr">République populaire de Chine</country>
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<author><name sortKey="Chen, Chun Bao" sort="Chen, Chun Bao" uniqKey="Chen C" first="Chun-Bao" last="Chen">Chun-Bao Chen</name>
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<author><name sortKey="Jiao, Rong" sort="Jiao, Rong" uniqKey="Jiao R" first="Rong" last="Jiao">Rong Jiao</name>
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<author><name sortKey="Zhang, Ai Ming" sort="Zhang, Ai Ming" uniqKey="Zhang A" first="Ai-Ming" last="Zhang">Ai-Ming Zhang</name>
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<author><name sortKey="Wang, Jin Tang" sort="Wang, Jin Tang" uniqKey="Wang J" first="Jin-Tang" last="Wang">Jin-Tang Wang</name>
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<author><name sortKey="Ding, Xi Wei" sort="Ding, Xi Wei" uniqKey="Ding X" first="Xi-Wei" last="Ding">Xi-Wei Ding</name>
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<country xml:lang="fr">République populaire de Chine</country>
<wicri:regionArea>Department of Pediatrics, Shiyan People's Hospital, Shiyan, 442000</wicri:regionArea>
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<author><name sortKey="Zeng, Yao Guang" sort="Zeng, Yao Guang" uniqKey="Zeng Y" first="Yao-Guang" last="Zeng">Yao-Guang Zeng</name>
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<country xml:lang="fr">République populaire de Chine</country>
<wicri:regionArea>Department of Pediatrics, Huanggang Central Hospital, Huanggang, 438000</wicri:regionArea>
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<author><name sortKey="Cheng, Li Ping" sort="Cheng, Li Ping" uniqKey="Cheng L" first="Li-Ping" last="Cheng">Li-Ping Cheng</name>
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<country xml:lang="fr">République populaire de Chine</country>
<wicri:regionArea>Department of Pediatrics, Huanggang Central Hospital, Huanggang, 438000</wicri:regionArea>
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<author><name sortKey="Huang, Qing Feng" sort="Huang, Qing Feng" uniqKey="Huang Q" first="Qing-Feng" last="Huang">Qing-Feng Huang</name>
<affiliation wicri:level="1"><nlm:affiliation>Department of Pediatrics, Jiangling People's Hospital, Jingzhou, 434101, China.</nlm:affiliation>
<country xml:lang="fr">République populaire de Chine</country>
<wicri:regionArea>Department of Pediatrics, Jiangling People's Hospital, Jingzhou, 434101</wicri:regionArea>
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<author><name sortKey="Wu, Jiang" sort="Wu, Jiang" uniqKey="Wu J" first="Jiang" last="Wu">Jiang Wu</name>
<affiliation wicri:level="1"><nlm:affiliation>Huangshi Maternity and Child Health Care Hospital, Huangshi, 435000, China.</nlm:affiliation>
<country xml:lang="fr">République populaire de Chine</country>
<wicri:regionArea>Huangshi Maternity and Child Health Care Hospital, Huangshi, 435000</wicri:regionArea>
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<author><name sortKey="Luo, Xi Chang" sort="Luo, Xi Chang" uniqKey="Luo X" first="Xi-Chang" last="Luo">Xi-Chang Luo</name>
<affiliation wicri:level="1"><nlm:affiliation>Huangshi Maternity and Child Health Care Hospital, Huangshi, 435000, China.</nlm:affiliation>
<country xml:lang="fr">République populaire de Chine</country>
<wicri:regionArea>Huangshi Maternity and Child Health Care Hospital, Huangshi, 435000</wicri:regionArea>
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<author><name sortKey="Wang, Zhu Jun" sort="Wang, Zhu Jun" uniqKey="Wang Z" first="Zhu-Jun" last="Wang">Zhu-Jun Wang</name>
<affiliation wicri:level="1"><nlm:affiliation>Department of Pediatrics, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China.</nlm:affiliation>
<country xml:lang="fr">République populaire de Chine</country>
<wicri:regionArea>Department of Pediatrics, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022</wicri:regionArea>
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<author><name sortKey="Zhong, Yan Yan" sort="Zhong, Yan Yan" uniqKey="Zhong Y" first="Yan-Yan" last="Zhong">Yan-Yan Zhong</name>
<affiliation wicri:level="1"><nlm:affiliation>Department of Pediatrics, Huazhong University of Science and Technology Hospital, Wuhan, 430074, China.</nlm:affiliation>
<country xml:lang="fr">République populaire de Chine</country>
<wicri:regionArea>Department of Pediatrics, Huazhong University of Science and Technology Hospital, Wuhan, 430074</wicri:regionArea>
<wicri:noRegion>430074</wicri:noRegion>
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<author><name sortKey="Bai, Yan" sort="Bai, Yan" uniqKey="Bai Y" first="Yan" last="Bai">Yan Bai</name>
<affiliation wicri:level="1"><nlm:affiliation>Department of Pediatrics, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China. yanbaixh@hust.edu.cn.</nlm:affiliation>
<country xml:lang="fr">République populaire de Chine</country>
<wicri:regionArea>Department of Pediatrics, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022</wicri:regionArea>
<wicri:noRegion>430022</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Wu, Xiao Yan" sort="Wu, Xiao Yan" uniqKey="Wu X" first="Xiao-Yan" last="Wu">Xiao-Yan Wu</name>
<affiliation wicri:level="1"><nlm:affiliation>Department of Pediatrics, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China. xwu@hust.edu.cn.</nlm:affiliation>
<country xml:lang="fr">République populaire de Chine</country>
<wicri:regionArea>Department of Pediatrics, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022</wicri:regionArea>
<wicri:noRegion>430022</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Jin, Run Ming" sort="Jin, Run Ming" uniqKey="Jin R" first="Run-Ming" last="Jin">Run-Ming Jin</name>
<affiliation wicri:level="1"><nlm:affiliation>Department of Pediatrics, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China. jinrunm@qq.com.</nlm:affiliation>
<country xml:lang="fr">République populaire de Chine</country>
<wicri:regionArea>Department of Pediatrics, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022</wicri:regionArea>
<wicri:noRegion>430022</wicri:noRegion>
</affiliation>
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<sourceDesc><biblStruct><analytic><title xml:lang="en">Clinical Characteristics of Children with Coronavirus Disease 2019 in Hubei, China.</title>
<author><name sortKey="Zheng, Fang" sort="Zheng, Fang" uniqKey="Zheng F" first="Fang" last="Zheng">Fang Zheng</name>
<affiliation wicri:level="1"><nlm:affiliation>Department of Pediatrics, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China.</nlm:affiliation>
<country xml:lang="fr">République populaire de Chine</country>
<wicri:regionArea>Department of Pediatrics, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022</wicri:regionArea>
<wicri:noRegion>430022</wicri:noRegion>
</affiliation>
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<author><name sortKey="Liao, Chun" sort="Liao, Chun" uniqKey="Liao C" first="Chun" last="Liao">Chun Liao</name>
<affiliation wicri:level="1"><nlm:affiliation>Department of Pediatrics, Yichang No. 3 People's Hospital, Yichang, 443000, China.</nlm:affiliation>
<country xml:lang="fr">République populaire de Chine</country>
<wicri:regionArea>Department of Pediatrics, Yichang No. 3 People's Hospital, Yichang, 443000</wicri:regionArea>
<wicri:noRegion>443000</wicri:noRegion>
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<author><name sortKey="Fan, Qi Hong" sort="Fan, Qi Hong" uniqKey="Fan Q" first="Qi-Hong" last="Fan">Qi-Hong Fan</name>
<affiliation wicri:level="1"><nlm:affiliation>Department of Pediatrics, Jingzhou First People's Hospital, Jingzhou, 434000, China.</nlm:affiliation>
<country xml:lang="fr">République populaire de Chine</country>
<wicri:regionArea>Department of Pediatrics, Jingzhou First People's Hospital, Jingzhou, 434000</wicri:regionArea>
<wicri:noRegion>434000</wicri:noRegion>
</affiliation>
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<author><name sortKey="Chen, Hong Bo" sort="Chen, Hong Bo" uniqKey="Chen H" first="Hong-Bo" last="Chen">Hong-Bo Chen</name>
<affiliation wicri:level="1"><nlm:affiliation>Department of Pediatrics, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China.</nlm:affiliation>
<country xml:lang="fr">République populaire de Chine</country>
<wicri:regionArea>Department of Pediatrics, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022</wicri:regionArea>
<wicri:noRegion>430022</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Zhao, Xue Gong" sort="Zhao, Xue Gong" uniqKey="Zhao X" first="Xue-Gong" last="Zhao">Xue-Gong Zhao</name>
<affiliation wicri:level="1"><nlm:affiliation>Department of Pediatrics, Yichang No. 3 People's Hospital, Yichang, 443000, China.</nlm:affiliation>
<country xml:lang="fr">République populaire de Chine</country>
<wicri:regionArea>Department of Pediatrics, Yichang No. 3 People's Hospital, Yichang, 443000</wicri:regionArea>
<wicri:noRegion>443000</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Xie, Zhong Guo" sort="Xie, Zhong Guo" uniqKey="Xie Z" first="Zhong-Guo" last="Xie">Zhong-Guo Xie</name>
<affiliation wicri:level="1"><nlm:affiliation>Department of Pediatrics, Jingzhou First People's Hospital, Jingzhou, 434000, China.</nlm:affiliation>
<country xml:lang="fr">République populaire de Chine</country>
<wicri:regionArea>Department of Pediatrics, Jingzhou First People's Hospital, Jingzhou, 434000</wicri:regionArea>
<wicri:noRegion>434000</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Li, Xi Lin" sort="Li, Xi Lin" uniqKey="Li X" first="Xi-Lin" last="Li">Xi-Lin Li</name>
<affiliation wicri:level="1"><nlm:affiliation>Xishui People's Hospital, Huanggang, 438000, China.</nlm:affiliation>
<country xml:lang="fr">République populaire de Chine</country>
<wicri:regionArea>Xishui People's Hospital, Huanggang, 438000</wicri:regionArea>
<wicri:noRegion>438000</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Chen, Chun Xi" sort="Chen, Chun Xi" uniqKey="Chen C" first="Chun-Xi" last="Chen">Chun-Xi Chen</name>
<affiliation wicri:level="1"><nlm:affiliation>Xishui People's Hospital, Huanggang, 438000, China.</nlm:affiliation>
<country xml:lang="fr">République populaire de Chine</country>
<wicri:regionArea>Xishui People's Hospital, Huanggang, 438000</wicri:regionArea>
<wicri:noRegion>438000</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Lu, Xiao Xia" sort="Lu, Xiao Xia" uniqKey="Lu X" first="Xiao-Xia" last="Lu">Xiao-Xia Lu</name>
<affiliation wicri:level="1"><nlm:affiliation>Wuhan Children's Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430015, China.</nlm:affiliation>
<country xml:lang="fr">République populaire de Chine</country>
<wicri:regionArea>Wuhan Children's Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430015</wicri:regionArea>
<wicri:noRegion>430015</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Liu, Zhi Sheng" sort="Liu, Zhi Sheng" uniqKey="Liu Z" first="Zhi-Sheng" last="Liu">Zhi-Sheng Liu</name>
<affiliation wicri:level="1"><nlm:affiliation>Wuhan Children's Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430015, China.</nlm:affiliation>
<country xml:lang="fr">République populaire de Chine</country>
<wicri:regionArea>Wuhan Children's Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430015</wicri:regionArea>
<wicri:noRegion>430015</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Lu, Wei" sort="Lu, Wei" uniqKey="Lu W" first="Wei" last="Lu">Wei Lu</name>
<affiliation wicri:level="1"><nlm:affiliation>Department of Pediatrics, Yichang Central Hospital, Yichang, 443000, China.</nlm:affiliation>
<country xml:lang="fr">République populaire de Chine</country>
<wicri:regionArea>Department of Pediatrics, Yichang Central Hospital, Yichang, 443000</wicri:regionArea>
<wicri:noRegion>443000</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Chen, Chun Bao" sort="Chen, Chun Bao" uniqKey="Chen C" first="Chun-Bao" last="Chen">Chun-Bao Chen</name>
<affiliation wicri:level="1"><nlm:affiliation>Department of Pediatrics, Yichang Central Hospital, Yichang, 443000, China.</nlm:affiliation>
<country xml:lang="fr">République populaire de Chine</country>
<wicri:regionArea>Department of Pediatrics, Yichang Central Hospital, Yichang, 443000</wicri:regionArea>
<wicri:noRegion>443000</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Jiao, Rong" sort="Jiao, Rong" uniqKey="Jiao R" first="Rong" last="Jiao">Rong Jiao</name>
<affiliation wicri:level="1"><nlm:affiliation>Department of Pediatrics, Xiangyang First People's Hospital, Xiangyang, 441000, China.</nlm:affiliation>
<country xml:lang="fr">République populaire de Chine</country>
<wicri:regionArea>Department of Pediatrics, Xiangyang First People's Hospital, Xiangyang, 441000</wicri:regionArea>
<wicri:noRegion>441000</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Zhang, Ai Ming" sort="Zhang, Ai Ming" uniqKey="Zhang A" first="Ai-Ming" last="Zhang">Ai-Ming Zhang</name>
<affiliation wicri:level="1"><nlm:affiliation>Department of Pediatrics, Xiangyang First People's Hospital, Xiangyang, 441000, China.</nlm:affiliation>
<country xml:lang="fr">République populaire de Chine</country>
<wicri:regionArea>Department of Pediatrics, Xiangyang First People's Hospital, Xiangyang, 441000</wicri:regionArea>
<wicri:noRegion>441000</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Wang, Jin Tang" sort="Wang, Jin Tang" uniqKey="Wang J" first="Jin-Tang" last="Wang">Jin-Tang Wang</name>
<affiliation wicri:level="1"><nlm:affiliation>Department of Pediatrics, Shiyan People's Hospital, Shiyan, 442000, China.</nlm:affiliation>
<country xml:lang="fr">République populaire de Chine</country>
<wicri:regionArea>Department of Pediatrics, Shiyan People's Hospital, Shiyan, 442000</wicri:regionArea>
<wicri:noRegion>442000</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Ding, Xi Wei" sort="Ding, Xi Wei" uniqKey="Ding X" first="Xi-Wei" last="Ding">Xi-Wei Ding</name>
<affiliation wicri:level="1"><nlm:affiliation>Department of Pediatrics, Shiyan People's Hospital, Shiyan, 442000, China.</nlm:affiliation>
<country xml:lang="fr">République populaire de Chine</country>
<wicri:regionArea>Department of Pediatrics, Shiyan People's Hospital, Shiyan, 442000</wicri:regionArea>
<wicri:noRegion>442000</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Zeng, Yao Guang" sort="Zeng, Yao Guang" uniqKey="Zeng Y" first="Yao-Guang" last="Zeng">Yao-Guang Zeng</name>
<affiliation wicri:level="1"><nlm:affiliation>Department of Pediatrics, Huanggang Central Hospital, Huanggang, 438000, China.</nlm:affiliation>
<country xml:lang="fr">République populaire de Chine</country>
<wicri:regionArea>Department of Pediatrics, Huanggang Central Hospital, Huanggang, 438000</wicri:regionArea>
<wicri:noRegion>438000</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Cheng, Li Ping" sort="Cheng, Li Ping" uniqKey="Cheng L" first="Li-Ping" last="Cheng">Li-Ping Cheng</name>
<affiliation wicri:level="1"><nlm:affiliation>Department of Pediatrics, Huanggang Central Hospital, Huanggang, 438000, China.</nlm:affiliation>
<country xml:lang="fr">République populaire de Chine</country>
<wicri:regionArea>Department of Pediatrics, Huanggang Central Hospital, Huanggang, 438000</wicri:regionArea>
<wicri:noRegion>438000</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Huang, Qing Feng" sort="Huang, Qing Feng" uniqKey="Huang Q" first="Qing-Feng" last="Huang">Qing-Feng Huang</name>
<affiliation wicri:level="1"><nlm:affiliation>Department of Pediatrics, Jiangling People's Hospital, Jingzhou, 434101, China.</nlm:affiliation>
<country xml:lang="fr">République populaire de Chine</country>
<wicri:regionArea>Department of Pediatrics, Jiangling People's Hospital, Jingzhou, 434101</wicri:regionArea>
<wicri:noRegion>434101</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Wu, Jiang" sort="Wu, Jiang" uniqKey="Wu J" first="Jiang" last="Wu">Jiang Wu</name>
<affiliation wicri:level="1"><nlm:affiliation>Huangshi Maternity and Child Health Care Hospital, Huangshi, 435000, China.</nlm:affiliation>
<country xml:lang="fr">République populaire de Chine</country>
<wicri:regionArea>Huangshi Maternity and Child Health Care Hospital, Huangshi, 435000</wicri:regionArea>
<wicri:noRegion>435000</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Luo, Xi Chang" sort="Luo, Xi Chang" uniqKey="Luo X" first="Xi-Chang" last="Luo">Xi-Chang Luo</name>
<affiliation wicri:level="1"><nlm:affiliation>Huangshi Maternity and Child Health Care Hospital, Huangshi, 435000, China.</nlm:affiliation>
<country xml:lang="fr">République populaire de Chine</country>
<wicri:regionArea>Huangshi Maternity and Child Health Care Hospital, Huangshi, 435000</wicri:regionArea>
<wicri:noRegion>435000</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Wang, Zhu Jun" sort="Wang, Zhu Jun" uniqKey="Wang Z" first="Zhu-Jun" last="Wang">Zhu-Jun Wang</name>
<affiliation wicri:level="1"><nlm:affiliation>Department of Pediatrics, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China.</nlm:affiliation>
<country xml:lang="fr">République populaire de Chine</country>
<wicri:regionArea>Department of Pediatrics, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022</wicri:regionArea>
<wicri:noRegion>430022</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Zhong, Yan Yan" sort="Zhong, Yan Yan" uniqKey="Zhong Y" first="Yan-Yan" last="Zhong">Yan-Yan Zhong</name>
<affiliation wicri:level="1"><nlm:affiliation>Department of Pediatrics, Huazhong University of Science and Technology Hospital, Wuhan, 430074, China.</nlm:affiliation>
<country xml:lang="fr">République populaire de Chine</country>
<wicri:regionArea>Department of Pediatrics, Huazhong University of Science and Technology Hospital, Wuhan, 430074</wicri:regionArea>
<wicri:noRegion>430074</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Bai, Yan" sort="Bai, Yan" uniqKey="Bai Y" first="Yan" last="Bai">Yan Bai</name>
<affiliation wicri:level="1"><nlm:affiliation>Department of Pediatrics, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China. yanbaixh@hust.edu.cn.</nlm:affiliation>
<country xml:lang="fr">République populaire de Chine</country>
<wicri:regionArea>Department of Pediatrics, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022</wicri:regionArea>
<wicri:noRegion>430022</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Wu, Xiao Yan" sort="Wu, Xiao Yan" uniqKey="Wu X" first="Xiao-Yan" last="Wu">Xiao-Yan Wu</name>
<affiliation wicri:level="1"><nlm:affiliation>Department of Pediatrics, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China. xwu@hust.edu.cn.</nlm:affiliation>
<country xml:lang="fr">République populaire de Chine</country>
<wicri:regionArea>Department of Pediatrics, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022</wicri:regionArea>
<wicri:noRegion>430022</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Jin, Run Ming" sort="Jin, Run Ming" uniqKey="Jin R" first="Run-Ming" last="Jin">Run-Ming Jin</name>
<affiliation wicri:level="1"><nlm:affiliation>Department of Pediatrics, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China. jinrunm@qq.com.</nlm:affiliation>
<country xml:lang="fr">République populaire de Chine</country>
<wicri:regionArea>Department of Pediatrics, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022</wicri:regionArea>
<wicri:noRegion>430022</wicri:noRegion>
</affiliation>
</author>
</analytic>
<series><title level="j">Current medical science</title>
<idno type="eISSN">2523-899X</idno>
<imprint><date when="2020" type="published">2020</date>
</imprint>
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<front><div type="abstract" xml:lang="en">Since December 2019, COVID-19 has occurred unexpectedly and emerged as a health problem worldwide. Despite the rapidly increasing number of cases in subsequent weeks, the clinical characteristics of pediatric cases are rarely described. A cross-sectional multicenter study was carried out in 10 hospitals across Hubei province. A total of 25 confirmed pediatric cases of COVID-19 were collected. The demographic data, epidemiological history, underlying diseases, clinical manifestations, laboratory and radiological data, treatments, and outcomes were analyzed. Of 25 hospitalized patients with COVID-19, the boy to girl ratio was 1.27:1. The median age was 3 years. COVID-19 cases in children aged <3 years, 3.6 years, and ≥6-years patients were 10 (40%), 6 (24%), and 9 (36%), respectively. The most common symptoms at onset of illness were fever (13 [52%]), and dry cough (11 [44%]). Chest CT images showed essential normal in 8 cases (33.3%), unilateral involvement of lungs in 5 cases (20.8%), and bilateral involvement in 11 cases (45.8%). Clinical diagnoses included upper respiratory tract infection (n=8), mild pneumonia (n=15), and critical cases (n=2). Two critical cases (8%) were given invasive mechanical ventilation, corticosteroids, and immunoglobulin. The symptoms in 24 (96%) of 25 patients were alleviated and one patient had been discharged. It was concluded that children were susceptible to COVID-19 like adults, while the clinical presentations and outcomes were more favorable in children. However, children less than 3 years old accounted for majority cases and critical cases lied in this age group, which demanded extra attentions during home caring and hospitalization treatment.</div>
</front>
</TEI>
<pubmed><MedlineCitation Status="Publisher" Owner="NLM"><PMID Version="1">32207032</PMID>
<DateRevised><Year>2020</Year>
<Month>03</Month>
<Day>24</Day>
</DateRevised>
<Article PubModel="Print-Electronic"><Journal><ISSN IssnType="Electronic">2523-899X</ISSN>
<JournalIssue CitedMedium="Internet"><PubDate><Year>2020</Year>
<Month>Mar</Month>
<Day>24</Day>
</PubDate>
</JournalIssue>
<Title>Current medical science</Title>
<ISOAbbreviation>Curr Med Sci</ISOAbbreviation>
</Journal>
<ArticleTitle>Clinical Characteristics of Children with Coronavirus Disease 2019 in Hubei, China.</ArticleTitle>
<ELocationID EIdType="doi" ValidYN="Y">10.1007/s11596-020-2172-6</ELocationID>
<Abstract><AbstractText>Since December 2019, COVID-19 has occurred unexpectedly and emerged as a health problem worldwide. Despite the rapidly increasing number of cases in subsequent weeks, the clinical characteristics of pediatric cases are rarely described. A cross-sectional multicenter study was carried out in 10 hospitals across Hubei province. A total of 25 confirmed pediatric cases of COVID-19 were collected. The demographic data, epidemiological history, underlying diseases, clinical manifestations, laboratory and radiological data, treatments, and outcomes were analyzed. Of 25 hospitalized patients with COVID-19, the boy to girl ratio was 1.27:1. The median age was 3 years. COVID-19 cases in children aged <3 years, 3.6 years, and ≥6-years patients were 10 (40%), 6 (24%), and 9 (36%), respectively. The most common symptoms at onset of illness were fever (13 [52%]), and dry cough (11 [44%]). Chest CT images showed essential normal in 8 cases (33.3%), unilateral involvement of lungs in 5 cases (20.8%), and bilateral involvement in 11 cases (45.8%). Clinical diagnoses included upper respiratory tract infection (n=8), mild pneumonia (n=15), and critical cases (n=2). Two critical cases (8%) were given invasive mechanical ventilation, corticosteroids, and immunoglobulin. The symptoms in 24 (96%) of 25 patients were alleviated and one patient had been discharged. It was concluded that children were susceptible to COVID-19 like adults, while the clinical presentations and outcomes were more favorable in children. However, children less than 3 years old accounted for majority cases and critical cases lied in this age group, which demanded extra attentions during home caring and hospitalization treatment.</AbstractText>
</Abstract>
<AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Zheng</LastName>
<ForeName>Fang</ForeName>
<Initials>F</Initials>
<AffiliationInfo><Affiliation>Department of Pediatrics, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Liao</LastName>
<ForeName>Chun</ForeName>
<Initials>C</Initials>
<AffiliationInfo><Affiliation>Department of Pediatrics, Yichang No. 3 People's Hospital, Yichang, 443000, China.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Fan</LastName>
<ForeName>Qi-Hong</ForeName>
<Initials>QH</Initials>
<AffiliationInfo><Affiliation>Department of Pediatrics, Jingzhou First People's Hospital, Jingzhou, 434000, China.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Chen</LastName>
<ForeName>Hong-Bo</ForeName>
<Initials>HB</Initials>
<AffiliationInfo><Affiliation>Department of Pediatrics, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Zhao</LastName>
<ForeName>Xue-Gong</ForeName>
<Initials>XG</Initials>
<AffiliationInfo><Affiliation>Department of Pediatrics, Yichang No. 3 People's Hospital, Yichang, 443000, China.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Xie</LastName>
<ForeName>Zhong-Guo</ForeName>
<Initials>ZG</Initials>
<AffiliationInfo><Affiliation>Department of Pediatrics, Jingzhou First People's Hospital, Jingzhou, 434000, China.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Li</LastName>
<ForeName>Xi-Lin</ForeName>
<Initials>XL</Initials>
<AffiliationInfo><Affiliation>Xishui People's Hospital, Huanggang, 438000, China.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Chen</LastName>
<ForeName>Chun-Xi</ForeName>
<Initials>CX</Initials>
<AffiliationInfo><Affiliation>Xishui People's Hospital, Huanggang, 438000, China.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Lu</LastName>
<ForeName>Xiao-Xia</ForeName>
<Initials>XX</Initials>
<AffiliationInfo><Affiliation>Wuhan Children's Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430015, China.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Liu</LastName>
<ForeName>Zhi-Sheng</ForeName>
<Initials>ZS</Initials>
<AffiliationInfo><Affiliation>Wuhan Children's Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430015, China.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Lu</LastName>
<ForeName>Wei</ForeName>
<Initials>W</Initials>
<AffiliationInfo><Affiliation>Department of Pediatrics, Yichang Central Hospital, Yichang, 443000, China.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Chen</LastName>
<ForeName>Chun-Bao</ForeName>
<Initials>CB</Initials>
<AffiliationInfo><Affiliation>Department of Pediatrics, Yichang Central Hospital, Yichang, 443000, China.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Jiao</LastName>
<ForeName>Rong</ForeName>
<Initials>R</Initials>
<AffiliationInfo><Affiliation>Department of Pediatrics, Xiangyang First People's Hospital, Xiangyang, 441000, China.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Zhang</LastName>
<ForeName>Ai-Ming</ForeName>
<Initials>AM</Initials>
<AffiliationInfo><Affiliation>Department of Pediatrics, Xiangyang First People's Hospital, Xiangyang, 441000, China.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Wang</LastName>
<ForeName>Jin-Tang</ForeName>
<Initials>JT</Initials>
<AffiliationInfo><Affiliation>Department of Pediatrics, Shiyan People's Hospital, Shiyan, 442000, China.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Ding</LastName>
<ForeName>Xi-Wei</ForeName>
<Initials>XW</Initials>
<AffiliationInfo><Affiliation>Department of Pediatrics, Shiyan People's Hospital, Shiyan, 442000, China.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Zeng</LastName>
<ForeName>Yao-Guang</ForeName>
<Initials>YG</Initials>
<AffiliationInfo><Affiliation>Department of Pediatrics, Huanggang Central Hospital, Huanggang, 438000, China.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Cheng</LastName>
<ForeName>Li-Ping</ForeName>
<Initials>LP</Initials>
<AffiliationInfo><Affiliation>Department of Pediatrics, Huanggang Central Hospital, Huanggang, 438000, China.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Huang</LastName>
<ForeName>Qing-Feng</ForeName>
<Initials>QF</Initials>
<AffiliationInfo><Affiliation>Department of Pediatrics, Jiangling People's Hospital, Jingzhou, 434101, China.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Wu</LastName>
<ForeName>Jiang</ForeName>
<Initials>J</Initials>
<AffiliationInfo><Affiliation>Huangshi Maternity and Child Health Care Hospital, Huangshi, 435000, China.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Luo</LastName>
<ForeName>Xi-Chang</ForeName>
<Initials>XC</Initials>
<AffiliationInfo><Affiliation>Huangshi Maternity and Child Health Care Hospital, Huangshi, 435000, China.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Wang</LastName>
<ForeName>Zhu-Jun</ForeName>
<Initials>ZJ</Initials>
<AffiliationInfo><Affiliation>Department of Pediatrics, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Zhong</LastName>
<ForeName>Yan-Yan</ForeName>
<Initials>YY</Initials>
<AffiliationInfo><Affiliation>Department of Pediatrics, Huazhong University of Science and Technology Hospital, Wuhan, 430074, China.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Bai</LastName>
<ForeName>Yan</ForeName>
<Initials>Y</Initials>
<AffiliationInfo><Affiliation>Department of Pediatrics, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China. yanbaixh@hust.edu.cn.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Wu</LastName>
<ForeName>Xiao-Yan</ForeName>
<Initials>XY</Initials>
<AffiliationInfo><Affiliation>Department of Pediatrics, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China. xwu@hust.edu.cn.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Jin</LastName>
<ForeName>Run-Ming</ForeName>
<Initials>RM</Initials>
<AffiliationInfo><Affiliation>Department of Pediatrics, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China. jinrunm@qq.com.</Affiliation>
</AffiliationInfo>
</Author>
</AuthorList>
<Language>eng</Language>
<PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType>
</PublicationTypeList>
<ArticleDate DateType="Electronic"><Year>2020</Year>
<Month>03</Month>
<Day>24</Day>
</ArticleDate>
</Article>
<MedlineJournalInfo><Country>China</Country>
<MedlineTA>Curr Med Sci</MedlineTA>
<NlmUniqueID>101729993</NlmUniqueID>
<ISSNLinking>2523-899X</ISSNLinking>
</MedlineJournalInfo>
<CitationSubset>IM</CitationSubset>
<KeywordList Owner="NOTNLM"><Keyword MajorTopicYN="N">COVID-19</Keyword>
<Keyword MajorTopicYN="N">SARS-CoV-2</Keyword>
<Keyword MajorTopicYN="N">children</Keyword>
<Keyword MajorTopicYN="N">coronavirus</Keyword>
</KeywordList>
</MedlineCitation>
<PubmedData><History><PubMedPubDate PubStatus="received"><Year>2020</Year>
<Month>02</Month>
<Day>25</Day>
</PubMedPubDate>
<PubMedPubDate PubStatus="revised"><Year>2020</Year>
<Month>03</Month>
<Day>10</Day>
</PubMedPubDate>
<PubMedPubDate PubStatus="entrez"><Year>2020</Year>
<Month>3</Month>
<Day>25</Day>
<Hour>6</Hour>
<Minute>0</Minute>
</PubMedPubDate>
<PubMedPubDate PubStatus="pubmed"><Year>2020</Year>
<Month>3</Month>
<Day>25</Day>
<Hour>6</Hour>
<Minute>0</Minute>
</PubMedPubDate>
<PubMedPubDate PubStatus="medline"><Year>2020</Year>
<Month>3</Month>
<Day>25</Day>
<Hour>6</Hour>
<Minute>0</Minute>
</PubMedPubDate>
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<PublicationStatus>aheadofprint</PublicationStatus>
<ArticleIdList><ArticleId IdType="pubmed">32207032</ArticleId>
<ArticleId IdType="doi">10.1007/s11596-020-2172-6</ArticleId>
<ArticleId IdType="pii">10.1007/s11596-020-2172-6</ArticleId>
</ArticleIdList>
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<affiliations><list><country><li>République populaire de Chine</li>
</country>
</list>
<tree><country name="République populaire de Chine"><noRegion><name sortKey="Zheng, Fang" sort="Zheng, Fang" uniqKey="Zheng F" first="Fang" last="Zheng">Fang Zheng</name>
</noRegion>
<name sortKey="Bai, Yan" sort="Bai, Yan" uniqKey="Bai Y" first="Yan" last="Bai">Yan Bai</name>
<name sortKey="Chen, Chun Bao" sort="Chen, Chun Bao" uniqKey="Chen C" first="Chun-Bao" last="Chen">Chun-Bao Chen</name>
<name sortKey="Chen, Chun Xi" sort="Chen, Chun Xi" uniqKey="Chen C" first="Chun-Xi" last="Chen">Chun-Xi Chen</name>
<name sortKey="Chen, Hong Bo" sort="Chen, Hong Bo" uniqKey="Chen H" first="Hong-Bo" last="Chen">Hong-Bo Chen</name>
<name sortKey="Cheng, Li Ping" sort="Cheng, Li Ping" uniqKey="Cheng L" first="Li-Ping" last="Cheng">Li-Ping Cheng</name>
<name sortKey="Ding, Xi Wei" sort="Ding, Xi Wei" uniqKey="Ding X" first="Xi-Wei" last="Ding">Xi-Wei Ding</name>
<name sortKey="Fan, Qi Hong" sort="Fan, Qi Hong" uniqKey="Fan Q" first="Qi-Hong" last="Fan">Qi-Hong Fan</name>
<name sortKey="Huang, Qing Feng" sort="Huang, Qing Feng" uniqKey="Huang Q" first="Qing-Feng" last="Huang">Qing-Feng Huang</name>
<name sortKey="Jiao, Rong" sort="Jiao, Rong" uniqKey="Jiao R" first="Rong" last="Jiao">Rong Jiao</name>
<name sortKey="Jin, Run Ming" sort="Jin, Run Ming" uniqKey="Jin R" first="Run-Ming" last="Jin">Run-Ming Jin</name>
<name sortKey="Li, Xi Lin" sort="Li, Xi Lin" uniqKey="Li X" first="Xi-Lin" last="Li">Xi-Lin Li</name>
<name sortKey="Liao, Chun" sort="Liao, Chun" uniqKey="Liao C" first="Chun" last="Liao">Chun Liao</name>
<name sortKey="Liu, Zhi Sheng" sort="Liu, Zhi Sheng" uniqKey="Liu Z" first="Zhi-Sheng" last="Liu">Zhi-Sheng Liu</name>
<name sortKey="Lu, Wei" sort="Lu, Wei" uniqKey="Lu W" first="Wei" last="Lu">Wei Lu</name>
<name sortKey="Lu, Xiao Xia" sort="Lu, Xiao Xia" uniqKey="Lu X" first="Xiao-Xia" last="Lu">Xiao-Xia Lu</name>
<name sortKey="Luo, Xi Chang" sort="Luo, Xi Chang" uniqKey="Luo X" first="Xi-Chang" last="Luo">Xi-Chang Luo</name>
<name sortKey="Wang, Jin Tang" sort="Wang, Jin Tang" uniqKey="Wang J" first="Jin-Tang" last="Wang">Jin-Tang Wang</name>
<name sortKey="Wang, Zhu Jun" sort="Wang, Zhu Jun" uniqKey="Wang Z" first="Zhu-Jun" last="Wang">Zhu-Jun Wang</name>
<name sortKey="Wu, Jiang" sort="Wu, Jiang" uniqKey="Wu J" first="Jiang" last="Wu">Jiang Wu</name>
<name sortKey="Wu, Xiao Yan" sort="Wu, Xiao Yan" uniqKey="Wu X" first="Xiao-Yan" last="Wu">Xiao-Yan Wu</name>
<name sortKey="Xie, Zhong Guo" sort="Xie, Zhong Guo" uniqKey="Xie Z" first="Zhong-Guo" last="Xie">Zhong-Guo Xie</name>
<name sortKey="Zeng, Yao Guang" sort="Zeng, Yao Guang" uniqKey="Zeng Y" first="Yao-Guang" last="Zeng">Yao-Guang Zeng</name>
<name sortKey="Zhang, Ai Ming" sort="Zhang, Ai Ming" uniqKey="Zhang A" first="Ai-Ming" last="Zhang">Ai-Ming Zhang</name>
<name sortKey="Zhao, Xue Gong" sort="Zhao, Xue Gong" uniqKey="Zhao X" first="Xue-Gong" last="Zhao">Xue-Gong Zhao</name>
<name sortKey="Zhong, Yan Yan" sort="Zhong, Yan Yan" uniqKey="Zhong Y" first="Yan-Yan" last="Zhong">Yan-Yan Zhong</name>
</country>
</tree>
</affiliations>
</record>

Pour manipuler ce document sous Unix (Dilib)

EXPLOR_STEP=$WICRI_ROOT/Wicri/Sante/explor/CovidV2/Data/Ncbi/Merge

HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 001582 | SxmlIndent | more

HfdSelect -h $EXPLOR_AREA/Data/Ncbi/Merge/biblio.hfd -nk 001582 | SxmlIndent | more

Pour mettre un lien sur cette page dans le réseau Wicri

{{Explor lien
   |wiki=    Wicri/Sante
   |area=    CovidV2
   |flux=    Ncbi
   |étape=   Merge
   |type=    RBID
   |clé=     pubmed:32207032
   |texte=   Clinical Characteristics of Children with Coronavirus Disease 2019 in Hubei, China.
}}

Pour générer des pages wiki

HfdIndexSelect -h $EXPLOR_AREA/Data/Ncbi/Merge/RBID.i   -Sk "pubmed:32207032" \
       | HfdSelect -Kh $EXPLOR_AREA/Data/Ncbi/Merge/biblio.hfd   \
       | NlmPubMed2Wicri -a CovidV2

This area was generated with Dilib version V0.6.33.
Data generation: Sat Mar 28 17:51:24 2020. Site generation: Sun Jan 31 15:35:48 2021

	Serveur d'exploration Covid (26 mars)
	Attention, ce site est en cours de développement ! Attention, site généré par des moyens informatiques à partir de corpus bruts. Les informations ne sont donc pas validées.

Serveur d'exploration Covid (26 mars)

Clinical Characteristics of Children with Coronavirus Disease 2019 in Hubei, China.

Clinical Characteristics of Children with Coronavirus Disease 2019 in Hubei, China.

Source :

Abstract

Links toward previous steps (curation, corpus...)

Links to Exploration step

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri

Pour générer des pages wiki